Predicted Indirectly Recognizable HLA Epitopes Presented by HLA-DRB1 Are Related to HLA Antibody Formation During Pregnancy

By: Kirsten Geneugelijk, Gideon Hönger, Hanneke W. van Deutekom, Kirsten A. Thus, Can Keşmir, Irene Hösli, Stefan Schaub, Eric Spierings

Published: in American Journal of Transplantation 2015; 15(12):3112-22.

Patients: 229

Highlights:

  • PIRCHE-II related to formation of child-specific HLA antibodies during pregnancy
  • Confirmation of the PIRCHE-II concept outside of transplantation setting