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literature.
Solid Organ Transplant
Kidney
Application of HLA molecular level mismatching in ethnically diverse kidney transplant recipients receiving a steroid-sparing immunosuppression protocol
February 23, 2024
An Integrated Approach Using HLAMatchmaker and Pirche II for Epitopic Matching in Pediatric Kidney Transplant—A Romanian Single-Center Study
November 2, 2023
Association between PIRCHE-II scores and de novo allosensitization after reduction of immunosuppression during SARS-CoV-2 infection in kidney transplant recipients
March 8, 2023
Progress in kidney transplantation: The role for systems immunology
December 16, 2022
Dissecting the impact of molecular T-cell HLA mismatches in kidney transplant failure: A retrospective cohort study
November 24, 2022
Snowflake epitope matching correlates with child-specific antibodies during pregnancy and donor-specific antibodies after kidney transplantation
October 28, 2022
The number of donor HLA-derived T cell epitopes available for indirect antigen presentation determines the risk for vascular rejection after kidney transplantation
August 30, 2022
PIRCHE-II Scores Prove Useful As A Predictive Biomarker Among Kidney Transplant Recipients With Rejection: An Analysis Of Indication And Follow-Up Biopsies
August 17, 2022
Association of Predicted HLA T-Cell Epitope Targets and T Cell-Mediated Rejection After Kidney Transplantation
June 9, 2022
High PIRCHE Scores May Allow Risk Stratification of Borderline Rejection in Kidney Transplant Recipients
February 18, 2022
PIRCHE-II score strong predictor for dnDSA post kidney transplantation PIRCHE-II independent from antigen mismatch and HLAMatchmaker
February 18, 2022
T-Cell Epitopes Shared Between Immunizing HLA and Donor HLA Associate With Graft Failure After Kidney Transplantation
November 18, 2021
Computational Eurotransplant kidney allocation simulations demonstrate the feasibility and benefit of T-cell epitope matching
June 27, 2021
Intravenous immunoglobulins do not prove beneficial to reduce alloimmunity among kidney transplant recipients with BKV-associated nephropathy
June 25, 2021
Clinical Significance of Shared T Cell Epitope Analysis in Early De Novo Donor-Specific Anti-HLA Antibody Production After Kidney Transplantation and Comparison With Shared B cell Epitope Analysis
March 26, 2021
Donor/Recipient HLA Molecular Mismatch Scores Predict Primary Humoral and Cellular Alloimmunity in Kidney Transplantation
March 10, 2021
Risk factors, histopathological features, and graft outcome of transplant glomerulopathy in the absence of donor-specific HLA antibodies
March 3, 2021
Can PIRCHE-II Matching Outmatch Traditional HLA Matching?
February 26, 2021
Analysis of T and B Cell Epitopes to Predict the Risk of de novo Donor-Specific Antibody (DSA) Production After Kidney Transplantation: A Two-Center Retrospective Cohort Study
August 27, 2020
Critical evaluation of a possible role of HLA epitope matching in kidney transplantation
January 17, 2020
PIRCHE-II: an algorithm to predict indirectly recognizable HLA epitopes in solid organ transplantation
November 18, 2019
Relationship of distribution frequency of HLA antigen/antibody and PIRCHE score with DSA production and AMR occurrence
March 26, 2019
The clinical significance of epitope mismatch load in kidney transplantation: A multicentre study
June 15, 2018
PIRCHE-II Is Related to Graft Failure after Kidney Transplantation
March 5, 2018
Donor-Recipient Matching Based on Predicted Indirectly Recognizable HLA Epitopes Independently Predicts the Incidence of De Novo Donor-Specific HLA Antibodies Following Renal Transplantation
July 28, 2017
The Immunogenicity of HLA Class II Mismatches: The Predicted Presentation of Nonself Allo-HLA-Derived Peptide by the HLA-DR Phenotype of the Recipient Is Associated with the Formation of DSA
February 26, 2017
Predicted indirectly recognizable HLA epitopes presented by HLA-DR correlate with the de novo development of donor-specific HLA IgG antibodies after kidney transplantation
December 8, 2013
Heart
Immunologic Risk Stratification of Pediatric Heart Transplant Patients by Combining HlaMatchmaker and PIRCHE-II
March 29, 2022
Epitope scores are better predictors for dnDSA formation after KTX than classical antigen matching
December 14, 2021
HLA-DQ Mismatches Stimulate de novo Donor Specific Antibodies in Heart Transplant Recipients
April 17, 2020
Lung
Predictive value of molecular matching tools for the development of donor specific HLA-antibodies in patients undergoing lung transplantation
April 20, 2023
Formation of donor-specific antibodies depends on the epitope load of mismatched HLAs in lung transplant recipients: A retrospective single-center study
August 1, 2022
Liver
Assessment of HLA matching algorithm PIRCHE-II on liver transplantation outcomes
April 25, 2022
Impact of calcineurin inhibitor-free immunosuppression on de novo donor-specific antibody formation in liver transplant recipients
March 1, 2022
Predictive value of HLAMatchmaker and PIRCHE-II scores for de novo donor-specific antibody formation after adult and pediatric liver transplantation
May 16, 2020
Exploring predicted indirectly recognizable HLA epitopes (PIRCHE-II) in liver transplant recipients on calcineurin inhibitor-free maintenance immunosuppression. A retrospective single center study.
February 12, 2020
Class II Human Leukocyte Antigen Epitope Mismatch Predicts De Novo Donor-Specific Antibody Formation After Liver Transplantation
January 25, 2018
Pregnancy
Peptides Derived From Mismatched Paternal Human Leukocyte Antigen Predicted to Be Presented by HLA-DRB1, -DRB3/4/5, -DQ, and -DP Induce Child-Specific Antibodies in Pregnant Women
December 21, 2021
Predicted Indirectly Recognizable HLA Epitopes Presented by HLA-DRB1 Are Related to HLA Antibody Formation During Pregnancy
October 29, 2015
Pancreas
Eplet Mismatch Scores and De novo Donor-specific Antibody Development in Simultaneous Pancreas-Kidney Transplantation
December 31, 2020
Immunogenicity of anti-HLA antibodies in pancreas and islet transplantation
November 25, 2016
Stem Cell Transplant
9/10
Experimental Data on PIRCHE and T-Cell Reactivity: HLA-DPB1-Derived Peptides Identified by PIRCHE-I Show Binding to HLA-A*02:01 in vitro and T-Cell Activation in vivo
April 2, 2024
Donor selection in a pediatric stem cell transplantation cohort using PIRCHE and HLA‐DPB1 typing
December 18, 2020
Predicted Indirectly ReCognizable HLA Epitopes (PIRCHE) Are Associated with Poorer Outcome after Single Mismatch Unrelated Donor Stem Cell Transplantation: A Study of the Cooperative Transplant Study Group (KTS) of the German Group for Bone Marrow and Stem Cell Transplantation (DAG-KBT)
August 29, 2019
Exploratory Study of Predicted Indirectly ReCognizable HLA Epitopes in Mismatched Hematopoietic Cell Transplantations
April 24, 2019
Indirectly recognized HLA-C mismatches and their potential role in transplant outcome
May 12, 2014
11/12
Molecular disparity of HLA-DPB1 is associated with the development of subsequent solid cancer after allogeneic hematopoietic stem cell transplantation
February 4, 2023
Analysis of biological models to predict clinical outcomes based on HLA-DPB1 disparities in unrelated transplantation
September 14, 2021
Refinement of the Definition of Permissible HLA-DPB1 Mismatches with Predicted Indirectly ReCognizable HLA-DPB1 Epitopes
June 26, 2014
Haplo
Various approaches for accessing the influence of human leukocyte antigens disparity in haploidentical stem cell transplantation
March 6, 2022
The Predicted Indirectly Recognizable HLA Epitopes (PIRCHE) Score for HLA Class I Graft-Versus-Host Disparity Is Associated with Increased Acute Graft-Versus-Host Disease in Haploidentical Transplantation with Post-Transplant Cyclophosphamide
September 26, 2020
Predicted indirectly recognizable HLA epitopes are not associated with clinical outcomes after haploidentical hematopoietic stem cell transplantation
November 16, 2018
Method
PIRCHE application major versions 3 and 4 lead to equivalent T cell epitope mismatch scores in solid organ and stem cell transplantation modules
March 22, 2024
Snowflake: A deep learning-based human leukocyte antigen matching algorithm considering allele-specific surface accessibility
July 29, 2022
Refined HLA-DPB1 mismatch with molecular algorithms predicts outcomes in hematopoietic stem cell transplantation
April 1, 2022
HLA Matching in Pediatric Stem Cell Transplantation
October 28, 2019
Inaccuracies in epitope repertoire estimations when using multilocus allele‐level HLA genotype imputation tools
June 10, 2018
Matching donor and recipient based on predicted indirectly recognizable human leucocyte antigen epitopes
February 21, 2018
Computational Approaches to Facilitate Epitope-Based HLA Matching in Solid Organ Transplantation
February 12, 2017
Completion of HLA protein sequences by automated homology-based nearest-neighbor extrapolation of HLA database sequences
April 4, 2016
The number of T cell allo-epitopes associates with CD4+ and CD8+ T-cell infiltration in pediatric cutaneous GVHD
March 16, 2015
Predicting Alloreactivity in Transplantation
April 28, 2014