Donor-Recipient Matching Based on Predicted Indirectly Recognizable HLA Epitopes Independently Predicts the Incidence of De Novo Donor-Specific HLA Antibodies Following Renal Transplantation

By: Nils Lachmann, Matthias Niemann, Petra Reinke, Klemens Budde, Danilo Schmidt, Fabian Halleck, Axel Pruß, Constanze Schönemann, Eric Spierings, Oliver Staeck

Published: in American Journal of Transplantation 2017; 17(12):3076-3086.

Patients: 2787

Highlights:

• PIRCHE-II score strong predictor for dnDSA post kidney transplantation
• PIRCHE-II independent from antigen mismatch and HLAMatchmaker