Predictive value of HLAMatchmaker and PIRCHE-II scores for de novo donor-specific antibody formation after adult and pediatric liver transplantation

By:  Sarah Hamada, Jérôme Dumortier, Céline Thévenin, Georges-Philippe Pageaux, Stéphanie Faure, Olivier Guillaud, Olivier Boillot, Alain Lachaux, Dan-Adrian Luscalov, Valérie Dubois, Magdalena Meszaros

Published: in Transplant Immunology 2020; Volume 61, August 2020, 101306.

Patients: 407

Highlights:

  • Predictive performance of HLAMatchmaker and PIRCHE-II for dnDSA in LT recipients

  • DRB1 and DQB1 PIRCHE-II and HLAMatchmaker scores higher in adult and pediatric patients having dnDSA

  • HLAMatchmaker and PIRCHE-II good predictors for dnDSA formation after LT for HLA class II