The number of donor HLA-derived T cell epitopes available for indirect antigen presentation determines the risk for vascular rejection after kidney transplantation

By: by Michiel G. H. Betjes, Emma T. M. Peereboom, Henny G. Otten and Eric Spierings

Published: in Biology of Blood and Marrow Transplantation 2016; 22(1):170-3.  

Patients: 134

Highlights:

• PIRCHE influences outcome of umbilicial cord blood transplantation
• High PIRCHE-I promotes GvL
• High PIRCHE-II may impact GvHD