By: Castrezana-Lopez et al
Published: in Transplant Infectious Disease 2023; Online
Patients: 47
Highlights:
- Observational Cohort Study of 47 Kidney Transplant Recipients who underwent substantial reduction of maintenance immunosuppression during SARS-CoV-2 infection.
- HLA-derived epitope mismatches were calculated using the PIRCHE-II algorithm.
- Study concludes that the HLA-derived epitope mismatch load between donor and recipient influences the risk of de novo DSA development when immunosuppression is temporarily reduced.